Joe Joyce continues to remain active whilst waiting for a world title shot when he takes on Zhilei Zhang at the Copper Box Arena in London on April 15.
Joyce impressed on his last outing in September which saw him knockout former world champion Joseph Parker in what was a brutal contest.
"This is another cracker of a card that should be in keeping with the special night we all just enjoyed at Wembley," said promoter Frank Warren.
"We want to keep Big Joe busy while the heavyweight title scene unfolds but there can be no easy touches in a defence of his WBO Interim title.
"Zhilei Zhang is anything but an easy touch, he is a formidable powerhouse who can consider himself unlucky not to be still an unbeaten contender following his fight with Filip Hrgovic last year.
"Zhang being a southpaw ticks a significant box for Joe, with Usyk being a left-hander and Tyson carrying the ability to adopt either stance. That is what we want next for Joe and hopefully it will be a huge all-British collision against Tyson."
Zhang will be looking to bounce back from what was a dissapointing loss on the judges' scorecards to Filip Hrgovic last August in a fight which many believed the Chinese fighter had won.