The Bills top the AFC East despite a narrow defeat to the Los Angeles Rams in Week 14.
Not even Josh Allen's record six-touchdown performance could prevent the end of their seven-game winning streak as the Rams pulled off a 42-44 win.
They'll meet a Lions side whose winning streak is still going strong, as they made it eleven victories on the bounce by beating the Green Bay Packers 34-31 last Friday.
Here's everything you need to know about Detroit Lions vs. Buffalo Bills.
Detroit Lions vs. Buffalo Bills date, start time
This could be the game of the weekend and so fans won't want to miss it. Make sure you catch the 4:25pm ET start, or 3:25pm centrally, or if you're watching in the UK, it's a 9:25pm kick-off.
Both the Bills and the Lions sit top of their respective divisions and between they have only suffered four losses all season.
- Date: Sunday, December 15
- Kick-off: 4:25pm ET / 9:25pm GMT
Where is Detroit Lions vs. Buffalo Bills?
The game takes place at Ford Field in Detroit, Michigan.
Opened in 2002, the naming rights are held by the Ford Motor Company in a 20-year agreement with the NFL side.
How to watchDetroit Lions vs. Buffalo Bills on DAZN
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