RB Leipzig faces Liverpool in Bucharest in the first leg of their Champions League knockout tie on Tuesday, with Liverpool scrabbling to find form and solve their defensive injury crisis.
On the same night, Paris Saint-Germain returns to the scene of La Remontada, hoping to bring an advantage back to Paris in the second leg. Barcelona's Ronald Koeman will hope that Lionel Messi's resurgence continues on the pitch despite his off-field frustrations.
Wednesday sees Sevilla vs. Dortmund, who has confirmed that Borussia Monchengladbach manager Marco Rose will join them to replace Lucien Favre at the end of the season. Porto will face Cristiano Ronaldo's Juventus, who are desperate to win the Champions League again.
The following week features Premier League side Chelsea against La Liga table-toppers Atletico Madrid, current Champions League holders Bayern Munich will face Lazio. Atalanta is to take on Real Madrid, and Monchengladbach will entertain Pep Guardiola's Manchester City.
Here's the full schedule for all of the Champions League first knockout round, first leg fixtures, plus how to watch every game live.
Champions League last 16, first legs: Schedule, fixtures
| Date | Time (GMT/ET) | Match | Live stream |
| Feb. 16 | 8:00 p.m. / 3 p.m. | RB Leipzig vs. Liverpool | BT Sport/CBS All Access |
| Feb. 16 | 8:00 p.m. / 3 p.m | Barcelona vs. PSG | BT Sport/CBS All Access |
| Feb. 17 | 8:00 p.m. / 3 p.m | Sevilla vs. Dortmund | BT Sport/CBS All Access |
| Feb. 17 | 8:00 p.m. / 3 p.m | Porto vs. Juventus | BT Sport/CBS All Access |
| Feb. 23 | 8:00 p.m. / 3 p.m | Atletico Madrid vs. Chelsea | BT Sport/CBS All Access |
| Feb. 23 | 8:00 p.m. / 3 p.m | Lazio vs. Bayern Munich | BT Sport/CBS All Access |
| Feb. 24 | 8:00 p.m. / 3 p.m | Atalanta vs. Real Madrid | BT Sport/CBS All Access |
| Feb. 24 | 8:00 p.m. / 3 p.m | M'Gladbach vs. Man City | BT Sport/CBS All Access |
How to watch the Champions League in the UK and USA: TV and live stream
BT Sport has the UK rights to show the Champions League, and in the US the Champions League games are shown on CBS All Access.